Capturing the changes in the knowledge base underlying drug discovery and development in the 20th century and the adjustment of Bayer, Hoechst, Schering AG and E. Merck to the advent of modern biotechnology.
Iciar Dominguez Lacasa
Scientometrics,
No. 2,
2006
Abstract
The so-called biotechnology revolution has changed the institutional and knowledge environment of the pharmaceutical industry. The industry incumbents have faced the challenge of adjusting to the new conditions for innovation in drug discovery and development. Drawing on the theoretical framework of the organizational capabilities of the firm, this contribution aims at capturing the changes in the knowledge environment and exploring the adjustment of 4 German corporations (2 companies rooted in the coal tar dyestuff industry and 2 traditional pharmaceutical companies) to the advent of modern biotechnology. Despite the firm-specific capabilities in organic chemical synthesis, the representatives of the coal tar dyestuff industry seem to have been better able to adjust to the external discontinuity in their knowledge environment.The existence of research and development activities, the science-based research tradition together with interactions to access the extramural knowledge base of the firms seem to have been crucial in the perception and adoption of the new technological possibilities of biotechnology after the 1970s, rather than prior competence in biotechnology or the employees with the skills to develop the capabilities to exploit it.
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Human capital in transformation – The example of the new Länder
Ralf Müller
IWH Discussion Papers,
No. 126,
2000
Abstract
The human capital of a nation is highly correlated to its productivity. Thus, differences in human capital may be seen as one factor determining the productivity gap between East and West Germany. However, a disadvantage of East Germany with regard to hu-man capital only shows up as long as it concerns skills that are built up on the job, i.e., by learning by doing; even more, this disadvantage has been decreasing in the 1990's. In contrast, as long as it concerns skills that have been acquired through formal education, East Germany has a high level of human capital in comparison to West Germany. In general, the problem of East Germany’s human capital proves to be rather demand-sided. It may be due to East Germany’s low skill-intensive industry structure.
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